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Merck
CN

A9482

Sigma-Aldrich

Anti-ATG4C antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-APG4 autophagy 4 homolog C, Anti-APG4-C, Anti-APG4C, Anti-ATG4 autophagy related 4 homolog C, Anti-AUT-like 1, cysteine endopeptidase, Anti-AUT-like 3 cysteine indopeptidase, Anti-AUTL1, Anti-AUTL3, Anti-Autophagin-2, Anti-Autophagy-related cysteine endopeptidase 3

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~52 kDa

species reactivity

human

concentration

~1.0 mg/mL

technique(s)

western blot: 1-2 μg/mL using whole extract of HEK-293T cells expressing human ATG4C

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... ATG4C(84938)

General description

ATG4c is a cysteine protease involved in autophagy in S. Cervisiae.
Rabbit Anti-ATG4C antibody binds to amino acids 51-65 of human ATG4C.

Application

Rabbit Anti-ATG4C antibody can be used for western blot assays at 1-2μg/ml.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Paul Jara et al.
American journal of physiology. Lung cellular and molecular physiology, 308(6), L511-L522 (2015-01-13)
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Svetlana Bortnik et al.
Oncotarget, 7(41), 66970-66988 (2016-08-25)
Autophagy, a lysosome-mediated degradation and recycling process, functions in advanced malignancies to promote cancer cell survival and contribute to cancer progression and drug resistance. While various autophagy inhibition strategies are under investigation for cancer treatment, corresponding patient selection criteria for
Qian Li et al.
Autophagy, 11(8), 1293-1307 (2015-07-08)
Burkholderia pseudomallei is the causative agent of melioidosis, a disease with high mortality, which is prevalent in tropical regions of the world. A recent study shows that B. pseudomallei can survive inside mammalian cells because of its ability to actively

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