A9603
Anti-Aph-1aL antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
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About This Item
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 30 kDa
species reactivity
human
technique(s)
western blot: 2-4 μg/mL using whole extract of human kidney 293 cells transfected with human Aph-1aL
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... APH1A(51107)
General description
Aph-1aL is a γ secretase subunit that facilitates the cleavage of several integral membrane proteins such as β-APP and Notch. Aph-1aL abnormalities have been associated with the risk of Alzheimer′s disease.
Rabbit Anti-Aph-1aL antibody recognizes Aph-1aL (30 kDa). Additional bands at approx. 46kDa and 20kDa may be observed in some cell extracts, which may represent Aph-1aL aggregation and degradation products, respectively.
Rabbit Anti-Aph-1aL antibody recognizes Aph-1aL (30 kDa). Additional bands at approx. 46kDa and 20kDa may be observed in some cell extracts, which may represent Aph-1aL aggregation and degradation products, respectively.
This sequence is identical in mouse Aph-1aL and not found in Aph-1aS and Aph-1b.
Immunogen
synthetic peptide corresponding to amino acids 246-265 located at the C-terminus of human Aph-1aL.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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