AV01028
Anti-GSK3A antibody produced in rabbit
IgG fraction of antiserum
Synonym(s):
Anti-Glycogen synthase kinase 3 α
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
51 kDa
species reactivity
canine, pig, human, rat, bovine, mouse
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... GSK3A(2931)
General description
Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase that is involved in Wnt and PI3K signaling. GSK3A has been implicated in memory dysfunctions and neurodegeneration related to Alzheimer′s disease.
Rabbit Anti-GSK3A antibody recognizes bovine, human, mouse, and rat GSK3A.
Rabbit Anti-GSK3A antibody recognizes bovine, human, mouse, and rat GSK3A.
Immunogen
Synthetic peptide directed towards the N terminal region of human GSK3A
Application
Rabbit Anti-GSK3A antibody is suitable for use in western blot applications at 1.25μg/ml.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGK
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Karl Peter Giese
IUBMB life, 61(5), 516-521 (2009-04-25)
Abnormalities in molecular signalling have been implicated in neurodegeneration. It is emerging that glycogen synthase kinase-3 (GSK-3) is a key signalling molecule that induces neurodegeneration and deficits in memory formation related to Alzheimer's disease (AD). Early stages of AD are
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