AV02023
Anti-DIABLO antibody produced in rabbit
IgG fraction of antiserum
Synonym(s):
Anti-Diablo homolog (Drosophila)
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
21 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... DIABLO(56616)
General description
DIABLO is known to interact with mammalian IAP homolog A (MIHA, XIAP), MIHB, MIHC and OpIAP. Furthermore, DIABLO binds to IAPs and prevents them from blocking caspases, thereby inducing apoptosis.
Rabbit Anti-DIABLO antibody binds to human, bovine, pig, and canine DIABLO.
Rabbit Anti-DIABLO antibody binds to human, bovine, pig, and canine DIABLO.
Immunogen
Synthetic peptide directed towards the C terminal region of human DIABLO
Application
Rabbit Anti-DIABLO antibody can be used for western blot applications at 0.3125μg/ml.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: LVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRE
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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A M Verhagen et al.
Cell, 102(1), 43-53 (2000-08-10)
To identify proteins that bind mammalian IAP homolog A (MIHA, also known as XIAP), we used coimmuno-precipitation and 2D immobilized pH gradient/SDS PAGE, followed by electrospray ionization tandem mass spectrometry. DIABLO (direct IAP binding protein with low pI) is a
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