AV32195
Anti-DBP (AB2) antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Anti-D site of albumin promoter (albumin D-box) binding protein
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
34 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... DBP(1628)
General description
Albumin promoter (albumin D-box) D-site binding protein (DBP), a PAR basic region leucine zipper (bZIP) protein, is a transcription factor involved in the diurnal regulation of gene transcription in the brain, liver and kidney. It regulates the expression of proteins such as cholesterol 7 α-hydroxylase P450 gene (CYP7) and kisspeptins (Kiss1).
DBP is known to control the growth of liver cells.
Rabbit polyclonal anti-DBP reacts with bovine, canine, human, mouse, and rat D-site of albumin promoter (albumin D-box) binding proteins.
Immunogen
Synthetic peptide directed towards the N terminal region of human DBP
Application
Rabbit Anti-DBP can be used for western blot applications at a concentration of 0.5-5.0μg/ml. It can also be used for immunohistochemistry at 4-8μg/ml, using paraffin-embedded tissues.
Rabbit polyclonal anti-DBP is used to tag D site of albumin promoter (albumin D-box) binding protein for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of D site of albumin promoter (albumin D-box) binding protein in diurnal regulation of gene expression.
Biochem/physiol Actions
D-site-binding protein (DBP) is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGR
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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C R Mueller et al.
Cell, 61(2), 279-291 (1990-04-20)
The full-length cDNA for a transcriptional activator, DBP, that binds to the D site of the albumin promoter has been cloned. DBP belongs to a family of related transcription factors including Fos, Jun, CREB, and C/EBP, which share a conserved
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