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Merck
CN

AV35173

Sigma-Aldrich

Anti-P2RXL1 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Purinergic receptor P2X-like 1, orphan receptor

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About This Item

UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

47 kDa

species reactivity

rat, rabbit, horse, guinea pig, human, bovine

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... P2RXL1(9127)

General description

P2RXL1 is a P2X receptor that is expressed in skeletal muscles. It is regulated by p53 and associates with VE-cadherin in umbilical endothelial cells of humans.
Rabbit Anti-P2RXL1 antibody recognizes human, mouse, rat, bovine, canine, and chicken P2RXL1.

Immunogen

Synthetic peptide directed towards the N terminal region of human P2RXL1

Application

Rabbit Anti-P2RXL1 antibody is suitable for western blot applications at a concentration of 0.5 μg/ml.

Biochem/physiol Actions

P2RXL1 encodes a protein in the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. P2RXL1 is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: ERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTN

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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