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AV35246

Anti-KCNIP1 antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-Kv channel interacting protein 1

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

25 kDa

species reactivity

rat, mouse, bovine, human, guinea pig, horse, dog

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

NP_055407

UniProt accession no.

Q9NZI2-2

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... KCNIP1(30820)

General description

KCNIP1 is a Kv channel interacting protein that regulates the excitability of neuronal membranes and the K-flux by shortening the cardiac action potential.
Rabbit anti-KCNIP1 antibody reacts with pig, bovine, chicken, human, mouse, and rat KCNIP1.

Immunogen

Synthetic peptide directed towards the N terminal region of human KCNIP1

Application

Anti-KCNIP1 antibody is suitable for western blot (1.35 μg/ml) and IHC (4-8 μg/ml) applications.

Biochem/physiol Actions

KCNIP1 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Alternative splicing results in multiple transcript variant encoding different isoforms.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: FSSLQTKQRRPSKDKIEDELEMTMVCHRPEGLEQLEAQTNFTKRELQVLY

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
低风险生物材料

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Certificates of Analysis (COA)

Lot/Batch Number
QC4549

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Fabian Grammes et al.
BMC genomics, 13, 180-180 (2012-05-15)
Under-dimensioned hearts causing functional problems are associated with higher mortality rates in intensive Atlantic salmon aquaculture. Previous studies have indicated that tetradecylthioacetic acid (TTA) induces cardiac growth and also stimulates transcription of peroxisome proliferator activated receptors (PPAR) αand βin the

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