AV41642
Anti-AGER (AB1) antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Anti-Advanced glycosylation end product-specific receptor, Anti-MGC22357, Anti-RAGE
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
UNSPSC Code:
12352203
MDL number:
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
mol wt
38 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... AGER(177)
General description
The receptor for advanced glycation end products (RAGE or AGER), a member of the immunoglobulin superfamily, is involved in pathologies such as atherosclerosis, micro- and macrovascular diseases, inflammatory diseases and diabetes. RAGE binds advanced glycation end products (AGE) produced by non-enzymatic glycation or glyoxidation of proteins, lipids and nucleic acids.
Immunogen
The immunogen for anti-AGER antibody: synthetic peptide derected towards the C terminal of human AGER
Application
Anti-AGER (AB1) polyclonal antibody is used to tag advanced glycation end product receptor protein(s) for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. Anti-AGER (AB1) polyclonal antibody may be used to study the effects/roles of glycation and glyoxidation in cardiovascular disease and diabetes.
Biochem/physiol Actions
Anti-RAGE polyclonal antibody reacts with human advanced glycosylation end product-specific receptor (AGER).
Physical form
Lyophilized from PBS buffer with 2% sucrose
Other Notes
Synthetic peptide located within the following region: PSPQIHWMKDVSDLERGAGRTRRGGANCRLCGRIRAGNSSPGPGDPGRPG
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Rongzhen Jiang et al.
Journal of immunology (Baltimore, Md. : 1950), 193(10), 5000-5012 (2014-10-24)
High mobility group box 1 (HMGB1) plays an important role in the pathologic processes of endothelial permeability under oxidative stress. Trophoblast oxidative stress has been implicated in the pathophysiology of preeclampsia (PE). HMGB1 serum levels are increased in PE. However
Jae-Chul Lee et al.
Neurochemical research, 39(8), 1553-1563 (2014-06-02)
The receptor for advanced glycation end products (RAGE) is a multi-ligand receptor of the immunoglobulin superfamily that has been implicated in multiple neuronal and inflammatory stress processes. In this study, we examined changes in RAGE immunoreactivity and its protein levels
Anisuzzaman et al.
The Journal of clinical investigation, 124(10), 4429-4444 (2014-11-18)
Ticks are notorious hematophagous ectoparasites and vectors of many deadly pathogens. As an effective vector, ticks must break the strong barrier provided by the skin of their host during feeding, and their saliva contains a complex mixture of bioactive molecules
Julia Ranzinger et al.
Cell and tissue research, 357(3), 667-679 (2014-05-30)
The receptor for advanced glycation end-products (RAGE), a multiligand receptor of the immunoglobulin superfamily, takes part in various inflammatory processes. The role of this receptor in the context of intercellular communication, like nanotube (NT)-mediated interaction, is largely unknown. Here, we
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service