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Merck
CN

AV47011

Anti-MTCH1 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-CGI-64, Anti-MGC131998, Anti-Mitochondrial carrier homolog 1 (C. elegans), Anti-PIG60, Anti-PSAP

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
1

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

40 kDa

species reactivity

mouse, rabbit, rat, horse, bovine, human, dog, pig

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_055156

UniProt accession no.

Q9NZJ7-2

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MTCH1(23787)

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Immunogen

Synthetic peptide directed towards the C terminal region of human MTCH1

Application

Anti-MTCH1 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.

Biochem/physiol Actions

MTCH1 [Mitochondrial carrier homolog 1 (C. elegans)] gene encodes a multi-pass membrane protein that belongs to mitochondrial carrier family and is localized in mitochondrion inner membrane. MTCH1 stimulates apoptosis independent of the proapoptotic proteins Bax and Bak.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: NNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFA

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
QC17778

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Xuemin Xu et al.
The Journal of biological chemistry, 277(50), 48913-48922 (2002-10-16)
Recent studies have suggested a possible role for presenilin proteins in apoptotic cell death observed in Alzheimer's disease. The mechanism by which presenilin proteins regulate apoptotic cell death is not well understood. Using the yeast two-hybrid system, we previously isolated

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