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Merck
CN

AV50044

Sigma-Aldrich

Anti-MLSTD2 antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-DKFZp686A0370, Anti-DKFZp686P18247, Anti-FAR1, Anti-FLJ22728, Anti-FLJ33561

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

59 kDa

species reactivity

rabbit, dog, rat, human, horse, bovine, mouse

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MLSTD2(84188)

Immunogen

Synthetic peptide directed towards the N terminal region of human MLSTD2

Application

Anti-MLSTD2 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.

Biochem/physiol Actions

MLSTD2 is popularly known as fatty acyl CoA reductase 1 (FAR1) is a transmembrane protein involved in the rate-limiting step of plasmalogen synthesis. It supplies fatty alcohols and catalyzes the ether bond formation in the synthesis of ether glycerophospholipid.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: LRSCPKVNSVYVLVRQKAGQTPQERVEEVLSGKLFDRLRDENPDFREKII

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Masanori Honsho et al.
The Journal of biological chemistry, 288(48), 34588-34598 (2013-10-11)
Peroxisomal fatty acyl-CoA reductase 1 (Far1) is essential for supplying fatty alcohols required for ether bond formation in ether glycerophospholipid synthesis. The stability of Far1 is regulated by a mechanism that is dependent on cellular plasmalogen levels. However, the membrane

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