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Merck
CN

AV53749

Sigma-Aldrich

Anti-TSKS (AB2) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-TSKS1, Anti-Testis-specific kinase substrate

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

65 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TSKS(60385)

Immunogen

Synthetic peptide directed towards the middle region of human TSKS

Application

Anti-TSKS (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.

Biochem/physiol Actions

TSKS (testis-specific serine kinase substrate) gene encodes a 92 amino acid containing protein predominantly expressed in testis and at low levels in prostate, female breast, placenta, ovary and thymus. TSKS is localized to the centrioles of spermatids and spermatozoa and may play a role in the process of spermatogenesis or spermatid development. It also facilitates the testicular physiology and sperm function.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: ALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERS

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Bingfang Xu et al.
Developmental biology, 319(2), 201-210 (2008-05-23)
Centrosomal coiled-coil proteins paired with kinases play critical roles in centrosomal functions within somatic cells, however knowledge regarding gamete centriolar proteins is limited. In this study, the substrate of TSSK1 and 2, TSKS, was localized during spermiogenesis to the centrioles
Zhonglin Hao et al.
Molecular human reproduction, 10(6), 433-444 (2004-03-27)
Two members of the human testis-specific serine/threonine (Ser/Thr) kinase family, TSSK 1 and TSSK 2, were cloned and sequenced from a human testis adaptor-ligated cDNA library using a PCR strategy. Within the cDNA, open reading frames (ORF) were defined encoding

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