B1186
Binucleine 2
≥97% (HPLC)
Synonym(s):
N′-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethyliminoformamide
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About This Item
Empirical Formula (Hill Notation):
C13H11N5ClF
CAS Number:
Molecular Weight:
291.71
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C13H11ClFN5/c1-19(2)8-17-13-9(6-16)7-18-20(13)10-3-4-12(15)11(14)5-10/h3-5,7-8H,1-2H3/b17-8+
SMILES string
CN(C)\C=N\c1c(cnn1-c2ccc(F)c(Cl)c2)C#N
InChI key
MNCYLHJHZOUDLB-CAOOACKPSA-N
assay
≥97% (HPLC)
form
solid
solubility
DMSO: soluble >5 mg/mL, H2O: insoluble
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
Binucleine 2 is a cytokinesis inhibitor.
Cytokinesis inhibitor.
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Regulatory Information
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Chantal Roubinet et al.
Current biology : CB, 31(18), 3973-3983 (2021-07-24)
Although nuclei are the defining features of eukaryotes, we still do not fully understand how the nuclear compartment is duplicated and partitioned during division. This is especially the case for organisms that do not completely disassemble their nuclear envelope upon
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