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Merck
CN

B1186

Binucleine 2

≥97% (HPLC)

Synonym(s):

N′-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethyliminoformamide

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About This Item

Empirical Formula (Hill Notation):
C13H11N5ClF
CAS Number:
Molecular Weight:
291.71
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥97% (HPLC)
Form:
solid
Quality level:
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Quality Level

assay

≥97% (HPLC)

form

solid

solubility

DMSO: soluble >5 mg/mL, H2O: insoluble

storage temp.

2-8°C

SMILES string

CN(C)\C=N\c1c(cnn1-c2ccc(F)c(Cl)c2)C#N

InChI

1S/C13H11ClFN5/c1-19(2)8-17-13-9(6-16)7-18-20(13)10-3-4-12(15)11(14)5-10/h3-5,7-8H,1-2H3/b17-8+

InChI key

MNCYLHJHZOUDLB-CAOOACKPSA-N

Biochem/physiol Actions

Binucleine 2 is a cytokinesis inhibitor.
Cytokinesis inhibitor.

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Chantal Roubinet et al.
Current biology : CB, 31(18), 3973-3983 (2021-07-24)
Although nuclei are the defining features of eukaryotes, we still do not fully understand how the nuclear compartment is duplicated and partitioned during division. This is especially the case for organisms that do not completely disassemble their nuclear envelope upon

Global Trade Item Number

SKUGTIN
B1186-2MG04061833258583
B1186-5MG04061833258590

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