B131
8-Bromoguanosine-3′,5′-cyclomonophosphate sodium salt
Synonym(s):
8-Br-cGMP
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About This Item
Empirical Formula (Hill Notation):
C10H10BrN5NaO7P
CAS Number:
Molecular Weight:
446.08
UNSPSC Code:
12352204
EC Number:
256-993-8
Beilstein/REAXYS Number:
8378760
MDL number:
SMILES string
[Na+].NC1=Nc2c(nc(Br)n2[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)C(=O)N1
storage temp.
−20°C
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Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Zhijian Wang et al.
American journal of physiology. Renal physiology, 304(5), F543-F552 (2012-12-14)
We used the patch-clamp technique to examine the role of carbon monoxide (CO) in regulating Ca(2+)-activated big-conductance K (BK) channels in the principal cell of the cortical collecting duct (CCD). Application of CORM3 or CORM2, a CO donor, activated BK
Stephen M Downs
Molecular reproduction and development, 78(10-11), 778-794 (2011-09-29)
Cumulus cell-enclosed oocytes (CEO), denuded oocytes (DO), or dissected follicles were obtained 44-48 hr after priming immature mice (20-23 days old) with 5 IU or immature rats (25-27 days old) with 12.5 IU of equine chorionic gonadotropin, and exposed to a variety of
Praveen Shukla et al.
American journal of physiology. Heart and circulatory physiology, 303(12), H1418-H1425 (2012-10-23)
Melatonin inhibits nitric oxide (NO)-induced relaxation of coronary arteries. We tested the hypothesis that melatonin increases the phosphorylation of phosphodiesterase 5 (PDE5), which increases the activity of the enzyme and thereby decreases intracellular cGMP accumulation in response to NO and
N Kabbesh et al.
Veterinary journal (London, England : 1997), 192(3), 368-373 (2011-10-12)
The direct vasodilatory action of pentoxifylline (1-(5-oxohexyl)-3,7-dimethylxanthine) and its signalling pathway was evaluated in equine digital veins. Cumulative concentration-response curves to pentoxifylline (1 nM to 300 μM) were recorded in phenylephrine-precontracted equine digital vein rings under different experimental conditions. Relaxation
Ljiljana Nikolić et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 198(7), 525-540 (2012-04-27)
The spontaneously active Br neuron from the brain-subesophageal ganglion complex of the garden snail Helix pomatia rhythmically generates regular bursts of action potentials with quiescent intervals accompanied by slow oscillations of membrane potential. We examined the involvement of the Na(+)/K(+)
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