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About This Item
Form:
buffered aqueous glycerol solution
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in E. coli
Mol wt:
31 kDa
recombinant
expressed in E. coli
description
full-length murine Bad with an N-terminal histidine-tag.
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
31 kDa
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
mouse ... Bad(12015)
Biochem/physiol Actions
Bad, a pro-apoptotic factor, is a member of the Bcl-2 family. Cytokine-induced phosphorylation of Bad results in it being sequested in the cytosol. In the absence of cytokines such as interleukin 3 (IL-3), Bad dephosphorylation occurs, causing the release of cytochrome c from the mitochondria.
Bad, a pro-apoptotic factor, is a member of the Bcl-2 family; in the absence of cytokines such as interleukin 3 (IL-3), Bad dephosphorylation occurs, causing the release of cytochrome c from the mitochondria.
Physical form
Supplied as a solution in phosphate buffered saline containing 250 mM imidizole and 50% glycerol.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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