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Merck
CN

B2006

2,4′-Dibromoacetophenone

≥98% (HPLC), powder

Synonym(s):

4′-Bromophenacyl bromide

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About This Item

Linear Formula:
BrC6H4COCH2Br
CAS Number:
Molecular Weight:
277.94
EC Number:
202-783-6
UNSPSC Code:
12352103
MDL number:
Beilstein/REAXYS Number:
607604
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assay

≥98% (HPLC)

form

powder

color

yellow to brown

mp

108-110 °C (lit.)

storage temp.

2-8°C

SMILES string

BrCC(=O)c1ccc(Br)cc1

InChI

1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2

InChI key

FKJSFKCZZIXQIP-UHFFFAOYSA-N



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Rodrigo G Stábeli et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 142(3-4), 371-381 (2006-01-31)
MjTX-II, a myotoxic phospholipase A(2) (PLA(2)) homologue from Bothrops moojeni venom, was functionally and structurally characterized. The MjTX-II characterization included: (i) functional characterization (antitumoral, antimicrobial and antiparasitic effects); (ii) effects of structural modifications by 4-bromophenacyl bromide (BPB), cyanogen bromide (CNBr)
Youngjin Park et al.
Archives of insect biochemistry and physiology, 60(3), 105-115 (2005-10-20)
We report on a secretory phospholipase A2 (sPLA2) associated with membrane-enriched fractions prepared from hemocytes of the tobacco hornworms, Manduca sexta. Virtually no PLA2 activity was detected in serum of immunologically naive or bacterially challenged hornworms. PLA2 activity was detected
Daniela P Marchi-Salvador et al.
Biochimica et biophysica acta, 1794(11), 1583-1590 (2009-07-21)
For the first time, the structure of a catalytic inactive phospholipase A(2) homolog (Lys49-PLA(2)s) complexed with p-bromophenacyl bromide (BPB) has been solved by X-ray crystallography. Lys49-PLA(2)s are among the main components of Viperidae snake venoms, causing myonecrosis and other actions