B2144
Boc-Tyr-D-Ala-Gly
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About This Item
Empirical Formula (Hill Notation):
C19H27N3O7
CAS Number:
Molecular Weight:
409.43
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
storage temp.
−20°C
SMILES string
CC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(O)=O
Biochem/physiol Actions
Boc-Tyr-D-Ala-Gly is an N-terminal protected tripeptides useful in solid phase peptide synthesis (Boc-SPPS). Boc-Tyr-D-Ala-Gly may be used in the synthesis of opioid activity containing peptides such as biphalin molecule, enkephalins and tetrapeptide hydrazide.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Nigel P Pedersen et al.
Journal of neurophysiology, 106(2), 731-740 (2011-05-20)
The rostral ventromedial medulla (RVM) is an important site of opioid actions and forms part of an analgesic pathway that projects to the spinal cord. The neuronal mechanisms by which opioids act within this brain region remain unclear, particularly in
A molecular dynamics study on opioid activities of biphalin molecule.
Hsieh JY, Chiang TY, Chen JL, et al.
Journal of Molecular Biology, 17, 2455-2464 (2011)
M Schnölzer et al.
International journal of peptide and protein research, 40(3-4), 180-193 (1992-09-01)
Simple, effective protocols have been developed for manual and machine-assisted Boc-chemistry solid phase peptide synthesis on polystyrene resins. These use in situ neutralization [i.e. neutralization simultaneous with coupling], high concentrations (> 0.2 M) of Boc-amino acid-OBt esters plus base for