B2930
Bone Morphogenetic Protein Receptor IA/Fc Chimera human
>90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder
Synonym(s):
BMPR-IA
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About This Item
UNSPSC Code:
51111800
MDL number:
Biological source:
human
Recombinant:
expressed in NSO cells
Assay:
>90% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
subunit calculated mol wt ~41.5 kDa
Impurities:
endotoxin, tested
biological source
human
recombinant
expressed in NSO cells
assay
>90% (SDS-PAGE)
form
lyophilized powder
potency
0.1-0.3 mg per mL ED50
mol wt
subunit calculated mol wt ~41.5 kDa
packaging
pkg of 100 μg
storage condition
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... BMPR1A(657)
Biochem/physiol Actions
BMPR-IA, also known as activin receptor-like kinase (ALK)-3, is a type I serine/theonine kinase which is required for the signal transduction of the TGF-β family cytokines. Human and murine bone morphogenetic protein receptor IA demonstrates 98% homology.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5.0 mg bovine serum albumin.
Analysis Note
The biological activity is measured by its ability to inhibit recombinant human BMP-4-induced alkaline phosphatase production in C2C12 cells.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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