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Merck
CN

B3559

Sigma-Aldrich

Biotinyl-Melanin-Concentrating Hormone from salmon

Synonym(s):

MCH Biotinylated

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About This Item

Empirical Formula (Hill Notation):
C99H153N29O26S5
Molecular Weight:
2325.78
MDL number:
MFCD00168126
UNSPSC Code:
12352200
PubChem Substance ID:
329773218

Key Documents

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form

solid

solubility

water: soluble

shipped in

ambient

storage temp.

−20°C

SMILES string

CSCC[C@@H]1NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](NC1=O)C(C)C)C(C)C)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCSC)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)CCCC[C@@H]6SC[C@@H]7NC(=O)N[C@H]67)[C@@H](C)O

InChI

1S/C99H153N29O26S5/c1-48(2)75-91(148)110-44-72(132)111-57(20-14-34-106-96(100)101)82(139)124-76(49(3)4)92(149)119-63(40-52-26-28-54(130)29-27-52)85(142)117-62(22-16-36-108-98(104)105)94(151)128-37-17-23-69(128)90(147)121-68(89(146)118-64(41-53-43-109-56-19-11-10-18-55(53)56)86(143)114-59(30-31-73(133)134)83(140)125-77(50(5)6)95(152)153)47-159-158-46-67(88(145)115-61(33-39-156-9)84(141)123-75)120-80(137)58(21-15-35-107-97(102)103)113-81(138)60(32-38-155-8)116-93(150)78(51(7)129)126-87(144)65(42-74(135)136)112-71(131)25-13-12-24-70-79-66(45-157-70)122-99(154)127-79/h10-11,18-19,26-29,43,48-51,57-70,75-79,109,129-130H,12-17,20-25,30-42,44-47H2,1-9H3,(H,110,148)(H,111,132)(H,112,131)(H,113,138)(H,114,143)(H,115,145)(H,116,150)(H,117,142)(H,118,146)(H,119,149)(H,120,137)(H,121,147)(H,123,141)(H,124,139)(H,125,140)(H,126,144)(H,133,134)(H,135,136)(H,152,153)(H4,100,101,106)(H4,102,103,107)(H4,104,105,108)(H2,122,127,154)/t51-,57+,58+,59+,60+,61+,62+,63+,64+,65+,66+,67+,68+,69+,70+,75+,76+,77+,78+,79+/m1/s1

InChI key

FKLSNVGEODBRRJ-KJQIIMNASA-N

Amino Acid Sequence

Biotinyl-Asp-Thr-Met-Arg-Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Glu-Val-OH [Disulfide bridge: 5-14]

Biochem/physiol Actions

Originally isolated from salmon pituitary glands, also found in the mammalian CNS. In lower vertebrates, MCH alters pigmentation by inducing melanosome aggregation within melanocytes of teleost fish, whereas it causes melanosome dispersion in amphibians and reptiles.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
122K1030

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