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Merck
CN

B5275

(+)-Brompheniramine maleate salt

Synonym(s):

Dexbrompheniramine maleate salt

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About This Item

Empirical Formula (Hill Notation):
C16H19BrN2 · C4H4O4
CAS Number:
2391-03-9
Molecular Weight:
435.31
UNSPSC Code:
12352200
PubChem Substance ID:
24278271
EC Number:
219-236-2
MDL number:
MFCD00072141

Key Documents

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InChI key

SRGKFVAASLQVBO-DASCVMRKSA-N

InChI

1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m0./s1

SMILES string

OC(=O)\C=C/C(O)=O.CN(C)CC[C@@H](c1ccc(Br)cc1)c2ccccn2

Gene Information

human ... HRH1(3269)

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Biochem/physiol Actions

Antihistamine; H1 histamine receptor antagonist.

Other Notes

Active isomer

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
031H0680

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J Sörbo et al.
International journal of experimental pathology, 75(1), 43-50 (1994-02-01)
The activation of mast-cells in situ induces angiogenesis in normally vascularized, adult mammalian tissue. Since the secreting mast-cell characteristically releases histamine, we studied the possible role of histamine in the outcome of mast-cell mediated angiogenesis using the rat mesenteric window
S U Yasuda et al.
Pharmacotherapy, 19(4), 447-451 (1999-04-22)
Anticholinergic effects are presumed to be the mechanism for the efficacy of chlorpheniramine in symptomatic relief of the common cold. Terfenadine, a second-generation antihistamine, reportedly lacks anticholinergic side effects. We evaluated affinities of two commonly used over-the-counter antihistamines, brompheniramine and

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