B5438
Balsalazide disodium salt hydrate
Synonym(s):
5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt hydrate
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About This Item
Empirical Formula (Hill Notation):
C17H13N3Na2O6 · xH2O
CAS Number:
Molecular Weight:
401.28 (anhydrous basis)
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.25
Assay
≥99% (HPLC)
form
powder
storage temp.
2-8°C
SMILES string
O.[Na+].[Na+].Oc1ccc(cc1C([O-])=O)\N=N\c2ccc(cc2)C(=O)NCCC([O-])=O
InChI
1S/C17H15N3O6.2Na.H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;1H2/q;2*+1;/p-2/b20-19+;;;
InChI key
ZZZXQZHSFPVNCR-HVARVCSCSA-L
Biochem/physiol Actions
Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals. Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa. It was also shown to inhibit azoxymethane-induced colon carcinogenesis. In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).
Storage Class Code
11 - Combustible Solids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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