B5667
5-Bromo-6-chloro-3-indolyl phosphate p-toluidine salt
~97% (HPLC)
Synonym(s):
Magenta™ phosphate
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About This Item
Empirical Formula (Hill Notation):
C8H6BrClNO4P · C7H9N
CAS Number:
Molecular Weight:
433.62
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
InChI
1S/C8H6BrClNO4P.C7H9N/c9-5-1-4-7(2-6(5)10)11-3-8(4)15-16(12,13)14;1-6-2-4-7(8)5-3-6/h1-3,11H,(H2,12,13,14);2-5H,8H2,1H3
SMILES string
Cc1ccc(N)cc1.OP(O)(=O)Oc2c[nH]c3cc(Cl)c(Br)cc23
InChI key
WUHVYTJTZAKPOS-UHFFFAOYSA-N
assay
~97% (HPLC)
form
powder
solubility
DMF: 50 mg/mL, clear, orange
storage temp.
−20°C
Quality Level
Legal Information
Magenta is a trademark of Merck KGaA, Darmstadt, Germany
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Dorota Rybaczek et al.
Histochemistry and cell biology, 135(3), 263-280 (2011-02-25)
Here, we demonstrate that in HeLa cells, Ser317 of Chk1 undergoes phosphorylation in response to replication stress induced by hydroxyurea. We also demonstrate the existence of constitutive (interphase and mitotic) Chk1 kinase phosphorylation, the translocation of its phosphorylated form from
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