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Merck
CN

B6781

Sigma-Aldrich

3-t-Butyl-5-methoxycatechol

Synonym(s):

3-t-Butyl-5-methoxy-1,2-benzenediol

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About This Item

Empirical Formula (Hill Notation):
C11H16O3
CAS Number:
Molecular Weight:
196.24
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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storage temp.

−20°C

SMILES string

COc1cc(O)c(O)c(c1)C(C)(C)C

InChI

1S/C11H16O3/c1-11(2,3)8-5-7(14-4)6-9(12)10(8)13/h5-6,12-13H,1-4H3

InChI key

CDUDTAOIPVCWDW-UHFFFAOYSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Y Nakagawa et al.
European journal of pharmacology, 270(4), 341-348 (1994-08-03)
The cytotoxic effects of 3-tert-butyl-4-hydroxyanisole (BHA) and its metabolites, 3-tert-butylhydroquinone (tBHQ) and 3-tert-butyl-4,5-dihydroxyanisole (BHA-OH), were investigated in freshly isolated rat hepatocytes. These compounds caused a time-dependent cell death accompanied by loss of intracellular ATP, glutathione (GSH) and protein thiols at
K E Armstrong et al.
Cancer research, 45(4), 1507-1510 (1985-04-01)
3-tert-Butylhydroxyanisole (3-BHA) is an antioxidant which can have a modulating effect on chemical carcinogenesis. Information concerning the metabolism of 3-BHA is incomplete. In the present study, the metabolites formed by incubating 3-BHA with liver microsomes from rats given beta-naphthoflavone by
A Sakai et al.
Carcinogenesis, 11(11), 1985-1988 (1990-11-01)
3-tert-Butyl-4-hydroxyanisole (3-BHA) and its metabolites, tert-butyl-1,4-benzoquinone (BQ) and 3-tert-butyl-5-methoxy-1,2-benzoquinone (BHAoQ), were tested for initiating activity in a two-stage transformation assay using BALB/3T3 cells. Cells were treated first with a test chemical and then with the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA).

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