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Merck
CN

B8651

3-Bromomethyl-6,7-dimethoxy-1-methyl-2(1H)-quinoxalinone

Synonym(s):

Br-DMEQ

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About This Item

Empirical Formula (Hill Notation):
C12H13BrN2O3
CAS Number:
Molecular Weight:
313.15
UNSPSC Code:
12171500
MDL number:
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storage temp.

2-8°C

SMILES string

COc1cc2N=C(CBr)C(=O)N(C)c2cc1OC

Application

Fluorescent derivatization reagent for carboxylic acids.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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M Konishi et al.
Journal of pharmaceutical sciences, 81(10), 1038-1041 (1992-10-01)
A high-performance liquid chromatographic (HPLC) method was developed for the determination of pivaloylcarnitine, one of the major metabolites of pivaloyloxymethyl (+)-(6R,7R)-7-[(Z)-2-(2-amino-4-thiazolyl)-2- pentenamido]-3-carbamoyloxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2- ene-2-carboxylate hydrochloride hydrate (S-1108), an oral cephem antibiotic, in human plasma and urine. Fluorescence detection was done
K Nakashima et al.
Journal of chromatography, 584(2), 275-279 (1992-12-23)
A sensitive high-performance liquid chromatographic method using 3-bromomethyl-6,7-dimethoxy-1-methyl-2(1H)-quinoxalinone (Br-DMEQ) as a fluorescent labeling reagent is described for the determination of benzoylecgonine (BE) and ecgonine (EC). The Br-DMEQ derivatives of BE and EC were separated on a C18 column and detected
Yamaguchi, M., et al.
Journal of Chromatography A, 346, 227-227 (1985)
M Yamaguchi et al.
Journal of chromatography, 414(2), 275-284 (1987-03-06)
A highly sensitive and rapid liquid chromatographic method for the determination of free and total phenylacetic and p- and m-hydroxyphenylacetic acids in human urine is described. After extraction of urine with diethyl ether, these acids and phenylpropionic acid (internal standard)
M J Nogueiras et al.
Analytical and bioanalytical chemistry, 377(7-8), 1202-1206 (2003-10-11)
The human toxic syndrome, diarrhetic shellfish poisoning (DSP), is caused by polyether toxins that are present in bivalve molluscs but originate from some species of marine phytoplankton. During the last few years different HPLC methods with fluorescence detection (FLD) have

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