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Merck
CN

BM0011

Sigma-Aldrich

Razaxaban hydrochloride

≥98% (HPLC)

Synonym(s):

1-(3-Amino-1,2-benzisoxazol-5-yl)-N-[4-[2-[(dimethylamino)methyl]-1H-imidazol-1-yl]-2-fluorophenyl]-3-(trifluoromethyl)-1H-Pyrazole-5-carboxamide hydrochloride, BMS 561389, BMS-561389

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About This Item

Empirical Formula (Hill Notation):
C24H20F4N8O2 · HCl
CAS Number:
405940-76-3
Molecular Weight:
564.92
MDL number:
MFCD25976560
UNSPSC Code:
12352200
PubChem Substance ID:
329774355
NACRES:
NA.77

Key Documents

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Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

SMILES string

O=C(NC1=CC=C(N2C(CN(C)C)=NC=C2)C=C1F)C3=CC(C(F)(F)F)=NN3C4=CC=C(ON=C5N)C5=C4.[H]Cl

InChI

1S/C24H20F4N8O2.ClH/c1-34(2)12-21-30-7-8-35(21)13-3-5-17(16(25)10-13)31-23(37)18-11-20(24(26,27)28)32-36(18)14-4-6-19-15(9-14)22(29)33-38-19;/h3-11H,12H2,1-2H3,(H2,29,33)(H,31,37);1H

InChI key

CASCTHHMARGRLB-UHFFFAOYSA-N

Biochem/physiol Actions

Razaxaban is an orally available, potent and specific coagulation factor Xa inhibitor that reduces thrombus and fibrin formation.
Razaxaban is an orally available, potent and specific coagulation factor Xa inhibitor that reduces thrombus and fibrin formation. Razaxaban exhibits potent antithrombotic efficacy in animal models and in patients with deep vein thrombosis.

Features and Benefits

Razaxaban is available through a partnership with Bristol-Myers Squibb (BMS). To learn more and view other BMS compounds, visit sigma.com/BMS.

Legal Information

Sold for research purposes only under agreement from BMS.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
076M4729V

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