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Merck
CN

BM0025

Sigma-Aldrich

BMS-538305 L-(+)-tartrate

≥98% (HPLC)

Synonym(s):

(1S,5R)-2-[(2S)-amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-Azabicyclo[3.1.0]hexane L-(+)-Tartaric acid salt, (2S)-2-Amino-1-(1S,5R)-2-azabicyclo[3.1.0]hex-2-yl-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-ethanone L-(+)-Tartaric acid salt, BMS 538305 tartarate, BMS-538305-06

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About This Item

Empirical Formula (Hill Notation):
C17H26N2O2 · C4H6O6
CAS Number:
Molecular Weight:
440.49
UNSPSC Code:
12352200
Form:
powder
Assay:
≥98% (HPLC)
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Assay

≥98% (HPLC)

form

powder

technique(s)

inhibition assay: suitable

color

white to beige

solubility

H2O: 20 mg/mL, clear

shipped in

ambient

storage temp.

room temp

General description

BMS-538305 is a saxagliptin analogue, without a nitrile group.

Biochem/physiol Actions

BMS-538305 is a potent and selective dipeptidyl peptidase IV (DPP-IV) inhibitor.
BMS-538305, a saxagliptin analog, is a potent and selective dipeptidyl peptidase IV (DPP-IV) inhibitor.

Features and Benefits

BMS-538305 is available through a partnership with Bristol-Myers Squibb (BMS). To learn more and view other BMS compounds, visit sigma.com/BMS.

Legal Information

Sold for research purposes only under agreement from BMS.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Involvement of DPP-IV catalytic residues in enzyme?saxagliptin complex formation.
Melzier, W.J., et al.
Protein Science, 17(2), 240-250 (2008)

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