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Merck
CN

C0290

Supelco

Clopamide

Synonym(s):

4-Chloro-N-(2,6-dimethylpiperidinyl)-3-sulfamoylbenzamide

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About This Item

Empirical Formula (Hill Notation):
C14H20ClN3O3S
CAS Number:
636-54-4
Molecular Weight:
345.84
EC Number:
211-261-7
MDL number:
MFCD00941495
UNSPSC Code:
41116107
PubChem Substance ID:
24892248

Key Documents

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technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H]1CCC[C@H](C)N1NC(=O)c2ccc(Cl)c(c2)S(N)(=O)=O

InChI

1S/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+

InChI key

LBXHRAWDUMTPSE-AOOOYVTPSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Precautionary Statements

P261 - P280 - P342 + P311

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
018F0915

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L A Piruzian et al.
Izvestiia Akademii nauk. Seriia biologicheskaia, (3)(3), 472-475 (1992-05-01)
The effect of 4-chlor-N-(cys-2,6-dimethyl peridine)-3-sulfomoin-benzamide as an anti-hypertensive drug on left-to-right hemisphere interactions was studied on experimental animals. Its effect on hemispheres was shown to be asymmetrical. The most effective action of the drug was demonstrated on the left hemisphere
[Use of viskaldix in the treatment of patients with hypertension].
R I Mikunis et al.
Klinicheskaia meditsina, 66(10), 62-64 (1988-10-01)
Stefan Bender et al.
The international journal of neuropsychopharmacology, 9(2), 135-145 (2005-09-22)
Accepted clinical evidence suggests superior efficacy of novel antipsychotics in the treatment of cognitive symptoms in schizophrenia. Whether this constitutes a primary drug effect or a secondary effect due to easing extrapyramidal side-effects or improving positive symptoms when converting from
D K Obatomi et al.
Cardiovascular drugs and therapy, 9(3), 407-412 (1995-06-01)
When choosing antihypertensive agents for the treatment of hypertension, it is necessary to consider the predisposition of individuals to renal damage, which may be associated with the long-term effect of such agents. In this respect, this study examined the effect
L Landriani et al.
Farmaco (Societa chimica italiana : 1989), 44(11), 1059-1068 (1989-11-01)
A series of N-(4-chloro-3-sulfamoylbenzamido)-1,2,3,4-tetrahydroquinoline++ + (IV-1) and isoquinoline (IV-2) have been synthesized and their diuretic and antihypertensive activities evaluated. While none of the test compounds was found to be provided with antihypertensive properties, most of them displayed a diuretic activity
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