Key Documents

View All Documentation

C0884

Coenzyme B₁₂

Name: Coenzyme B<SUB>12</SUB>
Brand: SIGMA

≥97.0%

Synonym(s):

5′-Deoxyadenosylcobalamine, Adenosyl cobalamine, Cobamamide, DMBC coenzyme

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₇₂H₁₀₀CoN₁₈O₁₇P

CAS Number:

13870-90-1

Molecular Weight:

1579.58

UNSPSC Code:

12352205

NACRES:

NA.79

PubChem Substance ID:

24892282

EC Number:

237-627-6

Beilstein/REAXYS Number:

4122932

MDL number:

MFCD00135609

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Segment

100

assay

≥97.0%

form

powder and chunks

technique(s)

HPLC: suitable

color

red to very dark red, very dark red-brown

storage temp.

−20°C

SMILES string

CC(CNC(=O)CCC1(C)C(CC(N)=O)C2N([Co+]C[C@H]3O[C@@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)C1=C(C)C6=NC(=CC7=NC(=C(C)C8=NC2(C)C(C)(CC(N)=O)C8CCC(N)=O)C(C)(CC(N)=O)C7CCC(N)=O)C(C)(C)C6CCC(N)=O)OP([O-])(=O)O[C@H]9[C@@H](O)[C@H](O[C@@H]9CO)n%10cnc%11cc(C)c(C)cc%10%11

InChI

1S/C62H90N13O14P.C10H12N5O3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);2-4,6-7,10,16-17H,1H2,(H2,11,12,13);/q;;+2/p-2/t31?,34?,35?,36?,37?,41-,52-,53-,56?,57+,59?,60?,61?,62?;4-,6-,7-,10+;/m11./s1

InChI key

ZIHHMGTYZOSFRC-PMDPKNCCSA-L

Description

General description

Vitamin B₁₂ cobalamin refers to a group of chemically-related cobalt containing molecules. The physiologically active forms of vitamin B₁₂ include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B_12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms.

Application

Coenzyme B₁₂ has been used as a supplement for culturing plasmid variants in in vivo assay of yvrC-lacZ fusions.

Biochem/physiol Actions

Vitamin B₁₂ cobalamin is involved in DNA synthesis and fatty acid synthesis. It also plays a vital role as a coenzyme in the conversion of mitochondrial methylmalonyl co-enzyme A to succinyl co-enzyme A.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKU	GTIN
C0884-100MG	04061833269428
C0884-250MG	04061833452400
C0884-25MG	04061833452424
C0884-1G	04061833452394

Key Documents

Coenzyme B₁₂

≥97.0%

Select a Size

About This Item

Quality Segment

assay

form

technique(s)

color

storage temp.

SMILES string

InChI

InChI key

General description

Application

Biochem/physiol Actions

Safety Information

Storage Class

wgk

flash_point_f

flash_point_c

ppe

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Product Citations

Global Trade Item Number

Key Documents

Coenzyme B12

≥97.0%

Select a Size

About This Item

Quality Segment

assay

form

technique(s)

color

storage temp.

SMILES string

InChI

InChI key

General description

Application

Biochem/physiol Actions

Safety Information

Storage Class

wgk

flash_point_f

flash_point_c

ppe

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Product Citations

Global Trade Item Number

Coenzyme B₁₂