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Merck
CN

C1044

Sigma-Aldrich

β-Calcitonin Gene Related Peptide human

≥97% (HPLC)

Synonym(s):

β-CGRP, CGRP-II

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About This Item

Empirical Formula (Hill Notation):
C162H267N51O48S3
CAS Number:
98824-26-1
Molecular Weight:
3793.36
MDL number:
MFCD00130617
UNSPSC Code:
51111800

Key Documents

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Assay

≥97% (HPLC)

composition

Peptide content, ~70%

UniProt accession no.

P10092

storage temp.

−20°C

Gene Information

human ... CALCB(797)

Amino Acid Sequence

Ala-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Met-Val-Lys-Ser-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 [Disulfide Bridge: 2-7]

Biochem/physiol Actions

Potent hypotensive agent and vasodilator.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
125H0094
120K1115
112K0539
084K0979
072K1208

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P H Steenbergh et al.
FEBS letters, 183(2), 403-407 (1985-04-22)
The calcitonin (CT) gene is alternatively expressed in a tissue-specific fashion producing either the calcium regulatory hormone CT in the thyroid or the neuropeptide calcitonin gene related peptide (CGRP) in the brain. In medullary carcinoma of the thyroid both peptides
P H Steenbergh et al.
FEBS letters, 209(1), 97-103 (1986-12-01)
Recently, we have reported the isolation of cDNA encoding a second human calcitonin gene-related peptide (hCGRP-II) [(1985) FEBS Lett. 183, 403-407]. In this report we describe the isolation and characterization of the gene encoding hCGRP-II. This gene, designated CALC-II, is

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