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C1115

Chrysamine G

≥95% (HPLC), ß-amyloid aggregates probe, solid

Synonym(s):

4,4′-Bis(3-carboxy-4-hydroxyphenylazo)biphenyl disodium salt

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About This Item

Empirical Formula (Hill Notation):
C26H16N4Na2O6
CAS Number:
6472-91-9
Molecular Weight:
526.41
UNSPSC Code:
12352116
PubChem Substance ID:
24724433
NACRES:
NA.77
MDL number:
MFCD00045823
Assay:
≥95% (HPLC)
Form:
solid
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Product Name

Chrysamine G, ≥95% (HPLC), solid

Quality Segment

100

assay

≥95% (HPLC)

form

solid

color

, orange to red to very dark brown

solubility

DMSO: ~4 mg/mL

storage temp.

−20°C

SMILES string

[Na+].[Na+].Oc1ccc(cc1C([O-])=O)N=Nc2ccc(cc2)-c3ccc(cc3)N=Nc4ccc(O)c(c4)C([O-])=O

InChI

1S/C26H18N4O6.2Na/c31-23-11-9-19(13-21(23)25(33)34)29-27-17-5-1-15(2-6-17)16-3-7-18(8-4-16)28-30-20-10-12-24(32)22(14-20)26(35)36;;/h1-14,31-32H,(H,33,34)(H,35,36);;/q;2*+1/p-2

InChI key

AZOPGDOIOXKJRA-UHFFFAOYSA-L

General description

Chrysamine G is a carboxylic acid derivative of Congo red.

Biochem/physiol Actions

Chrysamine G can penetrate the blood-brain barrier. It is useful in quantifying cerebral amyloid β (Aβ) deposition in Alzheimer′s disease (AD) pathological studies.
New probe for β-amyloid aggregates.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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