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C1131

Cytidine 5′-monophosphate

Name: Cytidine 5&#8242;-monophosphate
Brand: SIGMA

≥99% (HPLC), synthetic, powder

Synonym(s):

5′-CMP, 5′-Cytidylic acid, C-5′-P

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About This Item

Empirical Formula (Hill Notation):

C₉H₁₄N₃O₈P

CAS Number:

63-37-6

Molecular Weight:

323.20

NACRES:

NA.51

PubChem Substance ID:

24892358

UNSPSC Code:

41106305

EC Number:

200-556-6

MDL number:

MFCD00006544

Beilstein/REAXYS Number:

46982

Assay:

≥99% (HPLC)

Biological source:

synthetic

Form:

powder

Solubility:

1 M NH4OH: 50 mg/mL, clear, colorless

Storage temp.:

2-8°C

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Product Name

Cytidine 5′-monophosphate, Sigma Grade, ≥99% (HPLC), synthetic, powder

biological source

synthetic

Quality Level

200

grade

Sigma Grade

assay

≥99% (HPLC)

form

powder

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O

InChI

1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

InChI key

IERHLVCPSMICTF-XVFCMESISA-N

Related Categories

Biochemicals

Nucleosides and Nucleotides

Phosphates

Application

Cytidine 5′-monophosphate has been used in Raman spectroscopy studies.

Biochem/physiol Actions

The nucleoside diphosphates cytidine diphosphate (CDP) and uridine diphosphate (UDP) are essential for pyrimidine synthesis Cytidine 5′-monophosphate (CMP) nucleotide is useful in adsorption studies on biomimetic apatite for mimicking bone mineral. It also serves an immunity supplement in pediatric formulas.

Cytidine 5′-monophosphate (CMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Three families with hereditary hemolytic anemia and pyrimidine 5'-nucleotidase deficiency: electrophoretic and kinetic studies.

A Hirono et al.

Clinica chimica acta; international journal of clinical chemistry, 130(2), 189-197 (1983-05-30)

Three new variants of pyrimidine 5'-nucleotidase (P5N) found in Japan were studied. They are characterized by slow electrophoretic mobility and a high Michaelis constant for cytidine 5'-monophosphate as has been described in previously reported cases, but are unique with respect

Structure of the 2-aminopurine-cytosine base pair formed in the polymerase active site of the RB69 Y567A-DNA polymerase.

Linda J Reha-Krantz et al.

Biochemistry, 50(46), 10136-10149 (2011-10-26)

The adenine base analogue 2-aminopurine (2AP) is a potent base substitution mutagen in prokaryotes because of its enhanceed ability to form a mutagenic base pair with an incoming dCTP. Despite more than 50 years of research, the structure of the

Ultrafast IR spectroscopy of polymeric cytosine nucleic acids reveal the long-lived species is due to a localised state.

Páraic M Keane et al.

Physical chemistry chemical physics : PCCP, 14(18), 6307-6311 (2012-02-24)

The decay pathways of UV-excited cytosine polymers are investigated using picosecond time-resolved infrared spectroscopy. Similar yields of a non-emissive (1)nπ* state are found in the single-stranded dC(30) polymer as in the dCMP monomer, but with a longer lifetime in the

An enzymatic alternative for the synthesis of nucleoside 5?-monophosphates

Gudino ED, et al.

Enzyme and Microbial Technology, 111, 1-6 (2018)

Phosphatidylcholine biosynthesis and function in bacteria.

Otto Geiger et al.

Biochimica et biophysica acta, 1831(3), 503-513 (2012-08-28)

Phosphatidylcholine (PC) is the major membrane-forming phospholipid in eukaryotes and is estimated to be present in about 15% of the domain Bacteria. Usually, PC can be synthesized in bacteria by either of two pathways, the phospholipid N-methylation (Pmt) pathway or

View All Related Papers

Protocols

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

LC/MS Analysis of Nucleotides SeQuant^® ZIC^®-cHILIC – Effect of pH

ZIC^®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

Global Trade Item Number

SKU	GTIN
C1131-5G	04061833461259
C1131-500MG	04061833461235
C1131-1G	04061833461228

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