C1181
Carboxyethyl-γ-aminobutyric acid
≥80% (HPLC)
Synonym(s):
CEGABA
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About This Item
Empirical Formula (Hill Notation):
C7H13NO4
CAS Number:
Molecular Weight:
175.18
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C7H13NO4/c9-6(10)2-1-4-8-5-3-7(11)12/h8H,1-5H2,(H,9,10)(H,11,12)
SMILES string
OC(=O)CCCNCCC(O)=O
InChI key
SRGQUICKDUQCKO-UHFFFAOYSA-N
assay
≥80% (HPLC)
Biochem/physiol Actions
Cell growth promoter
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Vani Dos Santos Laranjeira et al.
Archives of dermatological research, 311(6), 491-497 (2019-05-16)
Cosmeceuticals are cosmetics formulated using compounds with medical-like benefits. Though the antiaging effect of carboxyethyl aminobutyric acid (CEGABA) has been discussed, its action mechanism in cosmeceuticals remains unclear. This study assessed the in vitro efficacy and safety of CEGABA. NHI-3T3
Pharmacological effects of CEGABA, a new aminoacid occurring in mammalian brain.
F Savoldi et al.
Il Farmaco; edizione scientifica, 42(1), 77-79 (1987-01-01)
P Bo et al.
Il Farmaco; edizione scientifica, 43(4), 363-372 (1988-04-01)
The central effects of carboxyethyl-gamma-aminobutyric acid (CEGABA) have been studied both in rabbits and in the guinea pig myoclonus model. This drug caused EEG synchronization and behavioural sedation both after intravenous (i.v.) and intracerebroventricular (i.c.v.) administration in a dose-dependent manner
A Cerino et al.
Biochemical and biophysical research communications, 150(3), 931-936 (1988-02-15)
A polyamine derivative, carboxyethyl - Aminobutyric Acid (CEGABA), induces the formation of a large number of Epstein-Barr Virus (EBV) transformed lymphocytes, when added to the culture medium immediately after EBV infection. However, CEGABA shows only a moderate effect on the
F Fussi et al.
Neuroscience letters, 77(3), 308-310 (1987-06-26)
The di-carboxylated derivative of spermidine, N-carboxyethyl gamma-aminobutyric acid (CEGABA) has been identified in bovine brain and human cerebrospinal fluid by HPLC. This discovery strongly suggests the existence of a metabolic pathway connecting polyamines and GABA via putreanine and CEGABA through
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