C121
7-Chlorokynurenic acid
solid
Synonym(s):
7-Chloro-4-hydroxyquinoline-2-carboxylic acid, 7-Cl-KYNA
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About This Item
Empirical Formula (Hill Notation):
C10H6ClNO3
CAS Number:
Molecular Weight:
223.61
UNSPSC Code:
12352200
EC Number:
241-913-6
MDL number:
SMILES string
OC(=O)c1cc(O)c2ccc(Cl)cc2n1
form
solid
color
tan
solubility
0.1 M NaOH: 13.7 mg/mL, DMSO: 14 mg/mL
Gene Information
human ... GRIN1(2902)
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Biochem/physiol Actions
Potent NMDA glutamate receptor antagonist; antagonizes the strychnine-insensitive glycine site of the NMDA receptor.
Potent NMDA glutamate receptor antagonist; antagonizes the strychnine-insensitive glycine site of the NMDA receptor; prevents neurodegeneration produced by quinolinic acid.
Regulatory Information
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