C1426
Cesium methanesulfonate
used in patch clamp techniques
Synonym(s):
CsMSF, CsMeS, Methanesulfonic acid cesium salt
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About This Item
Linear Formula:
CH3O3SCs
CAS Number:
Molecular Weight:
228.00
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25
Form:
powder
Quality Level
form
powder
mp
262-264 °C (lit.)
SMILES string
[Cs+].CS([O-])(=O)=O
InChI
1S/CH4O3S.Cs/c1-5(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1
InChI key
DJKJXRLREATOMF-UHFFFAOYSA-M
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General description
Cesium methanesulfonate is used as a component of intracellular recording solutions of electrodes for patch clamp techniques in cell electrophysiology studies. Cesium methanesulfonate is used as an current carrier as cesium acts as a potassium (K+) channel blocker, while methanesulfonate is not transported through chloride (Cl-) channels.
Application
Cesium methanesulfonate has been used as a supplement in intracellular solution for the patch clamp recording system.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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P L Li et al.
American journal of physiology. Heart and circulatory physiology, 280(1), H208-H215 (2000-12-21)
The present study was designed to test the hypothesis that cADP-ribose (cADPR) increases Ca(2+) release through activation of ryanodine receptors (RYR) on the sarcoplasmic reticulum (SR) in coronary arterial smooth muscle cells (CASMCs). We reconstituted RYR from the SR of
Diverse voltage-sensitive dyes modulate GABAA receptor function.
Mennerick., S., et al.
The Journal of Neuroscience, 24, 2871-2879 (2010)
An optogenetics- and imaging-assisted simultaneous multiple patch-clamp recording system for decoding complex neural circuits.
Wang G
Nature Protocols, 10, 397-397 (2015)
M Ouardouz et al.
Journal of neurophysiology, 77(4), 1939-1949 (1997-04-01)
Whole cell recordings were used in hippocampal slices of young rats to examine unitary inhibitory postsynaptic currents (uIPSCs) evoked in CA1 pyramidal cells at room temperature. Loose cell-attached stimulation was applied to activate single interneurons of different subtypes located in
D Mouginot et al.
Journal of neurophysiology, 75(2), 894-901 (1996-02-01)
1. Recording from deep cerebellar nuclei neurons, we investigated the role of presynaptic gamma-aminobutyric acid-B (GABAB) receptors in the modulation of monosynaptic inhibitory postsynaptic potentials (IPSPs) evoked by stimulation of Purkinje cells in rat slice cultures. 2. Bath application of
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