C154
nor-β-CFT
>96%, solid
Synonym(s):
(–)-2-β-Carbomethoxy-3-β-(4-fluorophenyl) nortropane
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About This Item
UNSPSC Code:
41116107
assay
>96%
form
solid
optical activity
[α]24/D −110.99°, c = 0.63 in chloroform(lit.)
drug control
USDEA Schedule II; Home Office Schedule 2; regulated under CDSA - not available from Sigma-Aldrich Canada
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
color
light yellow
solubility
DMSO: soluble
format
neat
storage temp.
−20°C
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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B K Madras et al.
Pharmacology, biochemistry, and behavior, 35(4), 949-953 (1990-04-01)
The binding properties of three N-modified fluorophenyltropane analogs of cocaine were compared in competition experiments with [3H]cocaine. All three analogs displaced specifically bound [3H]cocaine from caudate-putamen membranes of cynomolgus monkeys with affinities exceeding that of cocaine. The compound with the
R A Milius et al.
Journal of medicinal chemistry, 34(5), 1728-1731 (1991-05-01)
The synthesis and pharmacological characterization of a series of N-substituted 3-(4-fluorophenyl)tropane derivatives is reported. The compounds displayed binding characteristics that paralleled those of cocaine, and several had substantially higher affinity at cocaine recognition sites. Conjugate addition of 4-fluorophenyl magnesium bromide