C1676
μ-Conotoxin GIIIB
~95% (HPLC)
Synonym(s):
Arg-Asp-Cys-Cys-Thr-Hyp-Hyp-Arg-Lys-Cys-Lys-Asp-Arg-Arg-Cys-Lys-Hyp-Met-Lys-Cys-Cys-Ala-NH2 [Disulfide bridges undefined], GTXII, Geographutoxin II
Assay
~95% (HPLC)
composition
Peptide content, ~60%
storage temp.
−20°C
Biochem/physiol Actions
Vertebrate skeletal muscle Na+-channel blocker
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
S J Hong et al.
British journal of pharmacology, 97(3), 934-940 (1989-07-01)
1. Endplate potentials (e.p.ps) were investigated in the presence of geographutoxin II (GTXII) in the mouse phrenic nerve diaphragm preparation. This toxin preferentially blocks muscle Na+ channels which allows the study of e.p.ps in the absence of nicotinic receptor antagonists
Kubo, S., et al.
Peptide Chem., 1989, 257-257 (1990)
L J Cruz et al.
The Journal of biological chemistry, 260(16), 9280-9288 (1985-08-05)
We describe the properties of a family of 22-amino acid peptides, the mu-conotoxins, which are useful probes for investigating voltage-dependent sodium channels of excitable tissues. The mu-conotoxins are present in the venom of the piscivorous marine snail, Conus geographus L.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service