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C1788

(±)-Catechin hydrate

Name: (±)-Catechin hydrate
Brand: SIGMA

Synonym(s):

trans-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol, trans-3,3′,4′,5,7-Pentahydroxyflavane

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₄O₆ · xH₂O

CAS Number:

7295-85-4

Molecular Weight:

290.27 (anhydrous basis)

UNSPSC Code:

85151701

NACRES:

NA.79

PubChem Substance ID:

57653989

EC Number:

230-731-2

Beilstein/REAXYS Number:

92762

MDL number:

MFCD00149354

Assay:

≥96% (HPLC)

Form:

powder

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assay

≥96% (HPLC)

Quality Level

200

form

powder

technique(s)

HPLC: suitable

color

white to light brown

mp

200 °C (decomposes on heating)

storage temp.

2-8°C

SMILES string

[H]O[H].O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1

InChI key

OFUMQWOJBVNKLR-NQQJLSKUSA-N

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Biochemicals

Cell Culture Supplements & Reagents

Vitamins

General description

Catechin is produced by Cutch tree and is abundantly found in tea leaves, grape seeds, vegetables and plant-based beverages. It is a plant-derived, polyphenolic anti-oxidant and acts as a plant secondary metabolite.

Application

(±)-Catechin hydrate has been used:

to study its modulatory effect on drug resistance in human ovarian cancer cells
to construct the standard curve of total flavonoid content
to study its effects on the physiological parameters of Solanum lycopersicum

Biochem/physiol Actions

Catechin has phytotoxic properties. Racemic catechin may be used in studies on seed germination and plant invasiveness. Catechin and Epigallocatechin gallate (EGCG) may be used with other polyphenol flavonoids to study their effects in oxidation and peroxidation-related processes.

Polyphenolic antioxidant. Used in traditional Chinese medicine.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Oxidised LDL levels decreases after the consumption of ready-to-eat meals supplemented with cocoa extract within a hypocaloric diet.

I Ibero-Baraibar et al.

Nutrition, metabolism, and cardiovascular diseases : NMCD, 24(4), 416-422 (2014-01-28)

Cocoa flavanols are recognised by their favourable antioxidant and vascular effects. This study investigates the influence on health of the daily consumption of ready-to-eat meals supplemented with cocoa extract within a hypocaloric diet, on middle-aged overweight/obese subjects. Fifty healthy male

In vitro potential of phenolic phytochemicals from black rice on starch digestibility and rheological behaviors

An JS, et al.

Journal of Cereal Science, 70, 214-220 (2016)

The favourable effect of catechin in electrochemotherapy in human pancreatic cancer cells.

Olga Michel et al.

Acta biochimica Polonica, 65(2), 173-184 (2018-05-26)

Until recently, green tea polyphenols were considered strong antioxidants. However, the latest reports have revealed that bioflavonoids can play a multiple role in anticancer therapy, including the inhibition of cell proliferation and generation of the oxidative stress in a dose-dependent

The modulatory effect of green tea catechin on drug resistance in human ovarian cancer cells

Przystupski D, et al.

Medicinal Chemistry Research, 28(5), 657-667 (2019)

The use of a tannin crude extract from Cistus ladanifer L. to protect soya-bean protein from degradation in the rumen.

M T P Dentinho et al.

Animal : an international journal of animal bioscience, 1(5), 645-650 (2007-06-01)

Cistus ladanifer L. (CL) is a perennial shrub abundant in dry woods and dry land of Mediterranean zone, with high level of tannins. Tannins bind to protein, preventing its degradation in the digestive compartments. This tannin/protein complex may be advantageous

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Global Trade Item Number

SKU	GTIN
C1788-1G	04061833468043
C1788-5G	04061833468067
C1788-500MG	04061833468050

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