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Merck
CN

C212000

DMT-2′O-TBDMS-rC(tac) Phosphoramidite

Synonym(s):

DMT-2′-O-TBDMS-rC(tac) amidite, N-[[4-(1,1-dimethylethyl)phenoxy]acetyl]-5′-O-[bis(4-?methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-cytidine, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

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About This Item

Empirical Formula (Hill Notation):
C57H76N5O10PSi
CAS Number:
149989-66-2
Molecular Weight:
1050.30
PubChem Substance ID:
329774929
MDL number:
MFCD09842117

Key Documents

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InChI key

FAODNIJMAKFTFL-WSFKJFENSA-N

InChI

1S/C57H76N5O10PSi/c1-39(2)62(40(3)4)73(69-36-18-34-58)71-51-48(37-68-57(42-19-16-15-17-20-42,43-23-27-45(65-11)28-24-43)44-25-29-46(66-12)30-26-44)70-53(52(51)72-74(13,14)56(8,9)10)61-35-33-49(60-54(61)64)59-50(63)38-67-47-31-21-41(22-32-47)55(5,6)7/h15-17,19-33,35,39-40,48,51-53H,18,36-38H2,1-14H3,(H,59,60,63,64)/t48-,51-,52-,53-,73?/m1/s1

SMILES string

COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(=O)COc4ccc(cc4)C(C)(C)C)=NC3=O)(c5ccccc5)c6ccc(OC)cc6

product line

Proligo Reagents

assay

≥98% (31P-NMR), ≥98.0% (reversed phase HPLC)

technique(s)

oligo synthesis: suitable

λ

conforms (UV/VIS Identity)

nucleoside profile

base: cytidine
base protecting group: TAC
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: fast

storage temp.

−20°C

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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
HMBH9469
HMBH9082
HMBH8516
HMBH8182
HMBH8063

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