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Merck
CN

C212100

DMT-2′O-Methyl-rC(tac) Phosphoramidite

Synonym(s):

DMT-2′-O-Me-rC(tac) amidite, N-[[4-(1,1-dimethylethyl)phenoxy]acetyl]-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-cytidine, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

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About This Item

Empirical Formula (Hill Notation):
C52H64N5O10P
CAS Number:
Molecular Weight:
950.07
UNSPSC Code:
41116105
PubChem Substance ID:
MDL number:
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InChI

1S/C52H64N5O10P/c1-35(2)57(36(3)4)68(65-32-14-30-53)67-47-44(33-64-52(38-15-12-11-13-16-38,39-19-23-41(60-8)24-20-39)40-21-25-42(61-9)26-22-40)66-49(48(47)62-10)56-31-29-45(55-50(56)59)54-46(58)34-63-43-27-17-37(18-28-43)51(5,6)7/h11-13,15-29,31,35-36,44,47-49H,14,32-34H2,1-10H3,(H,54,55,58,59)/t44-,47-,48-,49-,68?/m1/s1

SMILES string

CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1N5C=CC(NC(=O)COc6ccc(cc6)C(C)(C)C)=NC5=O

InChI key

JRJMGDLRRSEUHM-MVHRPHEDSA-N

product line

Proligo Reagents

assay

≥98.0% (reversed phase HPLC), ≥99% (31P-NMR)

form

solid

technique(s)

oligo synthesis: suitable

λ

conforms (UV/VIS Identity)

nucleoside profile

base: cytidine
base protecting group: TAC
2' protecting group: methyl
5' protecting group: DMT
deprotection: fast

storage temp.

−20°C

Quality Level

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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