C3374
Cytochrome P450 Microsome Preparation human
3A4 Isozyme, recombinant, expressed in Saccharomyces cerevisiae, coexpressed with human NADPD reductase and human cytochrome b5
Synonym(s):
Cerosomes
concentration
15-25 mg protein/mL (Bradford assay)
biological source
human
recombinant
expressed in Saccharomyces cerevisiae
form
solution
specific activity
1.5-2.0 units/pmol enzyme
secondary activity
1300-1700 units/mg protein (Reductase activity)
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... CYP3A4(1576)
Looking for similar products? Visit Product Comparison Guide
Physical form
Supplied as a solution containing 50 mM potassium phosphate, pH 7.4, 5% glycerol, 1 mM EDTA, 1 mM PMSF, and 2 mM DTT
Analysis Note
CYP450 content: 40.0-60.0 picomoles per mg protein
Other Notes
For more more information visit our drug metabolism resources for Cytochrome P450 microsome preparations.
P450 Activity: One unit will oxidize 1.0 picomole of 7-benzoxymethyloxy-3-cyanocoumarin per minute at pH 7.4 at 37 °C.
Reductase Activity: One unit will reduce 1 nanomole of cytochrome c per minute in the presence of NADPH at pH 7.8 at 25 °C.
Reductase Activity: One unit will reduce 1 nanomole of cytochrome c per minute in the presence of NADPH at pH 7.8 at 25 °C.
Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service