Skip to Content
Merck
CN

C3490

Cyclofenil

≥98% (HPLC), white, solid

Synonym(s):

4,4′-Cyclohexylidenemethylenediphenol, 4-(Cyclohexylidenemethylene)-bis-phenol

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C23H24O4
CAS Number:
2624-43-3
Molecular Weight:
364.43
UNSPSC Code:
51111800
PubChem Substance ID:
329775038
EC Number:
220-089-1
MDL number:
MFCD00190153

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

GVOUFPWUYJWQSK-UHFFFAOYSA-N

InChI

1S/C23H24O4/c1-16(24)26-21-12-8-19(9-13-21)23(18-6-4-3-5-7-18)20-10-14-22(15-11-20)27-17(2)25/h8-15H,3-7H2,1-2H3

SMILES string

CC(=O)Oc1ccc(cc1)\C(=C2\CCCCC2)c3ccc(OC(C)=O)cc3

assay

≥98% (HPLC)

form

solid

color

white

solubility

DMSO: ≥10 mg/mL

storage temp.

2-8°C

Gene Information

human ... ESR1(2099), ESR2(2100)

Biochem/physiol Actions

Cyclofenil is a selective estrogen receptor β antagonist.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
038K4625
024K4621

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

D Drecktrah et al.
Journal of cell science, 111 ( Pt 7), 951-965 (1998-05-20)
Previous studies have shown that the Golgi stack and the trans-Golgi network (TGN) may play a role in capturing escaped resident endoplasmic reticulum (ER) proteins, and directing their retrograde transport back to that organelle. Whether this retrograde movement represents a
Hua Zhu et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 15(4), 591-599 (2010-03-03)
To develop technetium- and rhenium-labeled nonsteroidal estrogen imaging agents for estrogen receptor (ER) positive breast tumors, two groups of rhenium and technetium cyclofenil derivatives were synthesized and characterized. The binding affinities of the rhenium complexes for ERs were determined. The
Infertility and subfertility.
Kirsten Duckitt
Clinical evidence, (11)(11), 2427-2458 (2005-01-18)
Karen J Kieser et al.
Journal of medicinal chemistry, 53(8), 3320-3329 (2010-03-26)
Selective estrogen receptor (ER) down-regulators (SERDs) reduce ERalpha protein levels as well as block ER activity and therefore are promising therapeutic agents for the treatment of hormone refractory breast cancer. Starting with the triarylethylene acrylic acid SERD 4, we have
Peter Gärtner et al.
Journal of mass spectrometry : JMS, 43(7), 958-964 (2008-06-26)
The detection of metabolites of the anti-estrogenic substance cyclofenil, listed on the World Anti-Doping Agency (WADA) Prohibited List since 2004 is described. Target substances are hydroxylated metabolites, bearing an aliphatic hydroxyl group either in the 2-, 3- or 4-position of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service