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Merck
CN

C3987

Cardiotoxin 1 from Naja naja atra (Formosan Cobra)

Synonym(s):

CTX-1

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About This Item

CAS Number:
UNSPSC Code:
12352200
MDL number:
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mol wt

6,693 Da

storage temp.

−20°C

Biochem/physiol Actions

Cardiotoxin I is the component of the snake venom that is responsible for skeletal muscle necrosis. It also induces increases in capillary permeability that can be prevented by H1 histamine receptor antagonists, such as dephenhydramine, promethazine and cyproheptadine. This indicates that cardiotoxin may induce histamine release.
Component of the snake venom that is responsible for skeletal muscle necrosis.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Rujing Yang et al.
PloS one, 5(10), e13547-e13547 (2010-10-27)
Little is known about whether clones of ectopic, non-muscle stem cells contribute to muscle regeneration. Stem/progenitor cells that are isolated for experimental research or therapeutics are typically heterogeneous. Non-myogenic lineages in a heterogeneous population conceptually may compromise tissue repair. In
Jachinta E Rooney et al.
The American journal of pathology, 174(1), 256-264 (2008-12-17)
Mutations in the alpha7 integrin gene cause congenital myopathy characterized by delayed developmental milestones and impaired mobility. Previous studies in dystrophic mice suggest the alpha7beta1 integrin may be critical for muscle repair. To investigate the role that alpha7beta1 integrin plays

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