C4124
Chromium picolinate
≥98% (HPLC)
Synonym(s):
Cr(pic)3, CrPic
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About This Item
Empirical Formula (Hill Notation):
C18H12CrN3O6
CAS Number:
Molecular Weight:
418.30
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
biological source
synthetic
Quality Level
assay
≥98% (HPLC)
form
powder
loss
≤5% loss on drying
storage temp.
room temp
SMILES string
O=C(O[Cr](OC(=O)c1ccccn1)OC(=O)c2ccccn2)c3ccccn3
InChI
1S/3C6H5NO2.Cr/c3*8-6(9)5-3-1-2-4-7-5;/h3*1-4H,(H,8,9);/q;;;+3/p-3
InChI key
CBDQOLKNTOMMTL-UHFFFAOYSA-K
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General description
Chromium picolinate is a supplemental or alternative medication for type 2 diabetes and an anti-diabetic mechanisms of CrPic in insulin-resistant 3T3-L1 adipocytes.
Application
Chromium picolinate (CrPic), a dietay supplement, may be used to study its potential as a modulator of glucose uptake and the activity of insulin. CrPic is used to study its effects on nuclear factor-κ B (NF-κB) and nuclear factor-E2-related factor-2 (Nrf2) pathways in animals.
Biochem/physiol Actions
Chromium picolinate (CrPic) is a supplemental or alternative medication for type 2 diabetes. Experimental evidence shows the effect of CrPic on glucose uptake through the activation of p38 MAPK. Chromium is thought to potentiate the action of insulin, leading to increased insulin sensitivity in type 2 diabetes.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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C L Depew et al.
Journal of dairy science, 81(11), 2916-2923 (1998-12-05)
Forty-two Holstein calves were used to study performance and metabolic responses when milk replacer and then postweaning starter were supplemented with 1 ppm of Cr as Cr-tripicolinate. From birth through 8 wk of age, supplemental Cr tended to improve the
D J Appleton et al.
Journal of feline medicine and surgery, 4(1), 13-25 (2002-03-01)
The effect of dietary chromium supplementation on glucose and insulin metabolism in healthy, non-obese cats was evaluated. Thirty-two cats were randomly divided into four groups and fed experimental diets consisting of a standard diet with 0 ppb (control), 150 ppb
T L Ward et al.
Journal of animal science, 75(4), 1001-1008 (1997-04-01)
An experiment was conduct to determine the interactive effects of dietary chromium tripicolinate (CrPic), CP, and pen space (PS) as a stress on growth performance, carcass traits, and plasma hormones and metabolites of crossbred growing-finishing pigs (128 pigs; initial BW
E A Ott et al.
Journal of animal science, 77(11), 3022-3030 (1999-11-24)
Thoroughbred and Quarter Horse yearlings (n = 24; 335+/-7 d of age) were used in a 112-d feeding trial to determine whether chromium (Cr) supplementation would alter growth, development, and energy metabolism of growing horses on high-concentrate diets. The horses
C P A van de Ligt et al.
Journal of animal science, 80(2), 483-493 (2002-03-09)
Two experiments were conducted to evaluate potential interactive effects of supplemental Cr and dietary energy supply in growing pigs. Experiment 1 used 36 individually penned barrows, 25 to 65 kg, in a 2 x 3 factorial arrangement of supplemental Cr
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C4124-25G | 04061832407050 |
| C4124-5G | 04061833491669 |
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