C4714
Calreticulin from bovine liver
≥90% (SDS-PAGE), lyophilized powder
assay
≥90% (SDS-PAGE)
form
lyophilized powder
mol wt
~60 kDa
impurities
salt, essentially free
UniProt accession no.
storage temp.
−20°C
Gene Information
cow ... CALR(281036)
Biochem/physiol Actions
A high-affinity calcium binding protein which plays a dynamic role in calcium homeostasis. In addition, calreticulin binds directly to the DNA domain of hormone receptors as well as to the regulatory cytoplasmic domain of proteins of the integrin family. Calreticulin has also been shown to possess a chaperone function.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
I Wada et al.
The Journal of biological chemistry, 270(35), 20298-20304 (1995-09-01)
A unique type of chaperone that requires glucose trimming of the target proteins has been shown to be important for their maturation in the endoplasmic reticulum (ER). Calnexin, an ER membrane chaperone, is the first example of such a class.
Novel functions for calreticulin: interaction with integrins and modulation of gene expression?
S Dedhar
Trends in biochemical sciences, 19(7), 269-271 (1994-07-01)
L Mery et al.
The Journal of biological chemistry, 271(16), 9332-9339 (1996-04-19)
The widely distributed and highly conserved Ca(2+)-binding protein calreticulin has been suggested to play a role as a Ca2+ storage protein of intracellular Ca+ stores. To test this hypothesis, we have generated a mouse L fibroblast cell line stably transfected
K Burns et al.
Nature, 367(6462), 476-480 (1994-02-03)
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin has been
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service