C4806
Carbonic Anhydrase from human erythrocytes
mol wt
~29,000
pI
~7.0
shipped in
dry ice
storage temp.
−70°C
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Resp. Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Carbonic anhydrases.
Claudiu T Supuran
Bioorganic & medicinal chemistry, 21(6), 1377-1378 (2013-03-05)
Daisuke Fujiwara et al.
Biochemical and biophysical research communications, 434(4), 773-778 (2013-04-23)
In recent years, research on resistance to chemotherapy and radiotherapy in cancer treatment has come under the spotlight, and researchers have also begun investigating the relationship between resistance and cancer stem cells. Cancer stem cells are assumed to be present
Ben Y Zhang et al.
BJU international, 111(7), 1046-1053 (2013-04-05)
To evaluate carbonic anhydrase IX (CAIX) expression as an independent prognostic marker for clear cell renal cell carcinoma (ccRCC). With recent smaller studies showing conflicting results, we aimed to update our initial analysis in 2007 with an additional 5-year follow-up.
Anne Sinning et al.
FEBS letters, 587(13), 1923-1928 (2013-05-15)
As a general rule a rise in pH increases neuronal activity, whereas it is dampened by a fall of pH. Neuronal activity per se also challenges pH homeostasis by the increase of metabolic acid equivalents. Moreover, the negative membrane potential
Fabrizio Carta et al.
Journal of medicinal chemistry, 56(11), 4691-4700 (2013-05-08)
Dithiocarbamates (DTCs) were recently discovered as carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. A series of xanthates and a trithiocarbonate, structurally related to the DTCs, were prepared by reaction of alcohols/thiols with carbon disulfide in the presence of bases. These compounds
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