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Merck
CN

C6118

Sigma-Aldrich

Monoclonal Anti-Cdk5 antibody produced in mouse

~2 mg/mL, clone CDK-3G, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-Cyclin Dependent Kinase 5, Anti-PSSALRE

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About This Item

MDL number:
UNSPSC Code:
12352203
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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

CDK-3G, monoclonal

form

buffered aqueous solution

mol wt

~34 kDa

species reactivity

mouse, human

concentration

~2 mg/mL

technique(s)

indirect ELISA: suitable
western blot: 2-4 μg/mL using total cell extracts of mouse brain cytosolic fraction S1.

isotype

IgM

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... CDK5(1020)
mouse ... Cdk5(12568)

Immunogen

synthetic peptide corresponding to amino acids 269-285 of human Cdk5, conjugated to KLH.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Veronika Reiter et al.
Nucleic acids research, 40(13), 6235-6240 (2012-03-17)
The unusual cyclin-dependent protein kinase 5 (CDK5) was discovered based on its sequence homology to cell cycle regulating CDKs. CDK5 was found to be active in brain tissues, where it is not involved in cell cycle regulation but in the
Viviana Triaca et al.
Aging cell, 15(4), 661-672 (2016-04-15)
NGF has been implicated in forebrain neuroprotection from amyloidogenesis and Alzheimer's disease (AD). However, the underlying molecular mechanisms are still poorly understood. Here, we investigated the role of NGF signalling in the metabolism of amyloid precursor protein (APP) in forebrain

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