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Merck
CN

C6118

Monoclonal Anti-Cdk5 antibody produced in mouse

~2 mg/mL, clone CDK-3G, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-Cyclin Dependent Kinase 5, Anti-PSSALRE

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About This Item

UNSPSC Code:
12352203
MDL number:
MFCD00282840

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

CDK-3G, monoclonal

form

buffered aqueous solution

mol wt

~34 kDa

species reactivity

mouse, human

concentration

~2 mg/mL

technique(s)

indirect ELISA: suitable, western blot: 2-4 μg/mL using total cell extracts of mouse brain cytosolic fraction S1.

isotype

IgM

UniProt accession no.

Q00535

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... CDK5(1020)
mouse ... Cdk5(12568)

Immunogen

synthetic peptide corresponding to amino acids 269-285 of human Cdk5, conjugated to KLH.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
127K4797

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Veronika Reiter et al.
Nucleic acids research, 40(13), 6235-6240 (2012-03-17)
The unusual cyclin-dependent protein kinase 5 (CDK5) was discovered based on its sequence homology to cell cycle regulating CDKs. CDK5 was found to be active in brain tissues, where it is not involved in cell cycle regulation but in the
Viviana Triaca et al.
Aging cell, 15(4), 661-672 (2016-04-15)
NGF has been implicated in forebrain neuroprotection from amyloidogenesis and Alzheimer's disease (AD). However, the underlying molecular mechanisms are still poorly understood. Here, we investigated the role of NGF signalling in the metabolism of amyloid precursor protein (APP) in forebrain

Related Content

Data Sheet - C6118

Instructions

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