C6227
CART Fragment 61-102 rat, human
≥95%
Synonym(s):
Cocaine- and amphetamine-regulated transcript fragment 61-102
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About This Item
Empirical Formula (Hill Notation):
C189H310N58O56S7
Molecular Weight:
4515.29
MDL number:
UNSPSC Code:
51111800
Amino Acid Sequence
Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu
Biochem/physiol Actions
Satiety factor, closely associated with the actions of leptin and neuropeptide Y food intake regulators.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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E O Koylu et al.
Journal of neuroendocrinology, 9(11), 823-833 (1998-01-07)
CART peptide specific polyclonal antisera were raised in rabbits. The antisera were raised to CART peptide fragments that span most of the predicted CART protein. The specificity of each antisera was demonstrated by blockade of immunostaining by the immunizing peptide
Da Duan et al.
ACS chemical biology, 12(1), 282-290 (2016-12-17)
Colloidal aggregates of small molecules are the most common artifact in early drug discovery, sequestering and inhibiting target proteins without specificity. Understanding their structure and mechanism has been crucial to developing tools to control for, and occasionally even exploit, these
J Douglass et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 15(3 Pt 2), 2471-2481 (1995-03-01)
Neuronal plasticity associated with both short- and long-term administration of psychomotor stimulants involves alterations in specific patterns of gene expression. In order to screen for brain region specific mRNAs which are transcriptionally regulated by acute cocaine and amphetamine, PCR differential
J Douglass et al.
Gene, 169(2), 241-245 (1996-03-09)
PCR differential display screening has recently identified a rat mRNA termed CART (cocaine- and amphetamine-regulated transcript) which is transcriptionally regulated in the striatum following acute administration of psychomotor stimulants. The endogenous CART transcript is expressed in diverse rat brain structures
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