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Merck
CN

C6500

Cysteamine hydrochloride

new

suitable for cell culture

Synonym(s):

Cysteamine hydrochloride, β-Mercapto­ethylamine hydrochloride, 2-Amino­ethane­thiol hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, Decarboxy­cysteine hydrochloride, β-Mercapto­ethylamine hydrochloride, 2-Amino­ethane­thiol hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, Decarboxy­cysteine hydrochloride, Thio­ethanol­amine hydrochloride

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About This Item

Linear Formula:
HSCH2CH2NH2 · HCl
CAS Number:
156-57-0
Molecular Weight:
113.61
Beilstein:
3590083
MDL number:
MFCD00012904
UNSPSC Code:
12352202

Key Documents

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form

(Powder to crystal)

Quality Level

200

technique(s)

cell culture | mammalian: suitable

mp

67-71 °C

solubility

soluble (50mg/ml)

storage temp.

2-8°C

SMILES string

Cl[H].NCCS

InChI

1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H

InChI key

OGMADIBCHLQMIP-UHFFFAOYSA-N

General description

Cysteamine is a chemical compound that can be biosynthesized in mammals, including humans, by the degradation of coenzyme A. The intermediate pantetheine is broken down into cysteamine and pantothenic acid. It is the biosynthetic precursor to the neurotransmitter hypotaurine. It is a stable aminothiol, containing both an amine and a thiol functional groups. Cysteamine is a white, water-soluble solid. It is often used as salts of the ammonium derivative including the hydrochloride, phosphocysteamine, and the bitartrate.

Application

Cysteamine derived from cysteine degradation is the simplest stable aminothiol. Cysteamine is used in the biosynthesis of coenzyme A (CoA). Cysteamine may be useful in studies on oxidative stress and glycation (transglycating agent). Cysteamine is a substrate useful to study the specificity and kinetics of cysteamine (2-aminoethanethiol) dioxygenase(s) (ADO).

Features and Benefits

Cysteamine Hydrochloride or cysteamine is a mercaptoethylamine hydrochloride salt reductant that forms in mammals from pantetheine formation by degrading Coenzyme A. It has been used as a cystine depleting agent as well as a somatostatin inhibitor.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H317,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000491144
0000491144

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