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About This Item
Linear Formula:
HSCH2CH2NH2 · HCl
CAS Number:
Molecular Weight:
113.61
UNSPSC Code:
12352202
Beilstein/REAXYS Number:
3590083
MDL number:
NACRES:
NA.79
Product Name
Cysteamine hydrochloride, suitable for cell culture
InChI
1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H
SMILES string
Cl[H].NCCS
InChI key
OGMADIBCHLQMIP-UHFFFAOYSA-N
form
(Powder to crystal)
Quality Level
technique(s)
cell culture | mammalian: suitable
mp
67-71 °C
solubility
soluble (50mg/ml)
storage temp.
2-8°C
Application
Cysteamine derived from cysteine degradation is the simplest stable aminothiol. Cysteamine is used in the biosynthesis of coenzyme A (CoA). Cysteamine may be useful in studies on oxidative stress and glycation (transglycating agent). Cysteamine is a substrate useful to study the specificity and kinetics of cysteamine (2-aminoethanethiol) dioxygenase(s) (ADO).
Features and Benefits
Cysteamine Hydrochloride or cysteamine is a mercaptoethylamine hydrochloride salt reductant that forms in mammals from pantetheine formation by degrading Coenzyme A. It has been used as a cystine depleting agent as well as a somatostatin inhibitor.
General description
Cysteamine is a chemical compound that can be biosynthesized in mammals, including humans, by the degradation of coenzyme A. The intermediate pantetheine is broken down into cysteamine and pantothenic acid. It is the biosynthetic precursor to the neurotransmitter hypotaurine. It is a stable aminothiol, containing both an amine and a thiol functional groups. Cysteamine is a white, water-soluble solid. It is often used as salts of the ammonium derivative including the hydrochloride, phosphocysteamine, and the bitartrate.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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