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C7270

Cefamandole nafate

~95%

Synonym(s):

Cefamandole formate sodium salt

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About This Item

Linear Formula:
C19H17N6O6S2Na
CAS Number:
42540-40-9
Molecular Weight:
512.49
UNSPSC Code:
51101500
PubChem Substance ID:
24892951
EC Number:
255-877-4
MDL number:
MFCD00864877
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assay

~95%

mode of action

cell wall synthesis | interferes

SMILES string

[Na+].Cn1nnnc1SCC2=C(N3C(SC2)[C@H](NC(=O)[C@H](OC=O)c4ccccc4)C3=O)C([O-])=O

InChI

1S/C19H18N6O6S2.Na/c1-24-19(21-22-23-24)33-8-11-7-32-17-12(16(28)25(17)13(11)18(29)30)20-15(27)14(31-9-26)10-5-3-2-4-6-10;/h2-6,9,12,14,17H,7-8H2,1H3,(H,20,27)(H,29,30);/q;+1/p-1/t12-,14-,17-;/m1./s1

InChI key

ICZOIXFFVKYXOM-YCLOEFEOSA-M

General description

Chemical structure: β-lactam

Application

Cefamandole is used to study the effects of expression and inhibition of PBP 2A and other penicillin-binding proteins (PDPs) on bacterial cell wall mucopeptide synthesis.

Biochem/physiol Actions

Cefamandole nafate inhibits bacterial cell wall synthesis by inhibiting PBP 2A and other penicillin-binding proteins. Cefamandole nafate has been shown to be rapidly converted to cefamandolein bacteriological media .

Physical form

sodium carbonate: approx. 5%

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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