C7519
Choline bicarbonate
~80% in H2O
Synonym(s):
2-Hydroxyethyl)trimethylammonium bicarbonate
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About This Item
Linear Formula:
C5H14NO · HCO3
CAS Number:
Molecular Weight:
165.19
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
50501514
MDL number:
InChI
1S/C5H14NO.CH2O3/c1-6(2,3)4-5-7;2-1(3)4/h7H,4-5H2,1-3H3;(H2,2,3,4)/q+1;/p-1
SMILES string
OC([O-])=O.C[N+](C)(C)CCO
InChI key
DQKGOGJIOHUEGK-UHFFFAOYSA-M
form
liquid
concentration
~80% in H2O
density
1.17 g/mL at 25 °C (lit.)
lipid type
phospholipids
storage temp.
2-8°C
Quality Level
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General description
Choline acetyltransferase substrate
Application
Choline, a water soluble essential nutrient, is used by the body to make phosphatidylcholine phosphatides and neurotransmitter such as acetylcholine. Choline is used to study a wide range of biological processes from stem cell development to neurological disease studies. Also, An alkaline intermediate useful for preparing salts.
Biochem/physiol Actions
Acyl group acceptor
Other Notes
Note: The bicarbonate converts to the carbonate with release of CO2 on aging.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Diana Gómora-Herrera et al.
Applied spectroscopy, 72(4), 562-572 (2017-12-09)
The effects exerted by the adsorption of vapors of a non-polar compound (deuterated benzene) and a polar compound (water) on the surface of Ottawa sand and a sample of reservoir sand (Channel), which was previously impregnated with silicon oil or
Eden E L Tanner et al.
Journal of controlled release : official journal of the Controlled Release Society, 286, 137-144 (2018-07-22)
Transdermal delivery of pharmaceuticals using ionic liquids and deep eutectic solvents (DES) has attracted significant interest due to the inherent tunability of the molecules and their capacity to transport large molecules across the skin. Several key properties of DESs including
Vimisha Dharamdasani et al.
Journal of controlled release : official journal of the Controlled Release Society, 323, 475-482 (2020-04-28)
Skin diseases such as lupus, cancer, psoriasis, and hyperhidrosis can potentially be treated effectively by suppressing allele-specific genes using small interfering RNA (siRNA). Injections of siRNA into skin, though effective, are painful and cover small surface areas and thus are
Fred Elhi et al.
Molecules (Basel, Switzerland), 25(7) (2020-04-11)
Mixing ionic liquids is a suitable strategy to tailor properties, e.g., to reduce melting points. The present study aims to widen the application range of low-toxic choline-based ionic liquids by studying eight binary phase diagrams of six different choline carboxylates.
Louisa G Sylvia et al.
Psychotherapy and psychosomatics, 82(1), 10-19 (2012-11-14)
Pharmacotherapy is the first line of treatment for bipolar disorder, but many patients continue to experience persistent subthreshold symptoms. Alternative adjunct treatments, including nutritional therapies, may have the potential to alleviate residual symptoms and improve the outcomes of standard pharmacotherapy.
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