C8289
Clebopride maleate salt
~95%
Synonym(s):
4-(4-Amino-5-chloro-2-methoxybenzamido)-1-benzylpiperidine
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About This Item
Empirical Formula (Hill Notation):
C20H24ClN3O2 · C4H4O4
CAS Number:
Molecular Weight:
489.95
UNSPSC Code:
51101500
PubChem Substance ID:
MDL number:
assay
~95%
storage temp.
2-8°C
SMILES string
OC(=O)\C=C\C(O)=O.COc1cc(N)c(Cl)cc1C(=O)NC2CCN(CC2)Cc3ccccc3
InChI
1S/C20H24ClN3O2.C4H4O4/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14;5-3(6)1-2-4(7)8/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25);1-2H,(H,5,6)(H,7,8)/b;2-1+
InChI key
BCVIWCRZYPHHMQ-WLHGVMLRSA-N
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Product Information Sheet
Domenico Bosco et al.
Clinical neuropharmacology, 32(2), 107-108 (2009-06-11)
Dystonic reactions produce twisting and repetitive movements or abnormal posturing. Severe dystonic reactions have been shown to occur in concert with numerous medications. This report details the case of a patient who developed hemifacial dystonia as acute side reaction from
[Acute laryngeal dystonia due to clebopride simulating allergic reaction].
Mercè Corominas Sánchez et al.
Medicina clinica, 129(6), 238-239 (2007-08-07)
Jaume Campdelacreu et al.
Movement disorders : official journal of the Movement Disorder Society, 19(4), 482-484 (2004-04-13)
We report on a patient who presented with a progressive supranuclear palsy (PSP) syndrome while receiving clebopride (CLB), a prokinetic drug with central antidopaminergic properties. The clinical and neurophysiological signs progressively disappeared after CLB withdrawal. To our knowledge, this is