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Merck
CN

C8289

Clebopride maleate salt

~95%

Synonym(s):

4-(4-Amino-5-chloro-2-methoxybenzamido)-1-benzylpiperidine

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About This Item

Empirical Formula (Hill Notation):
C20H24ClN3O2 · C4H4O4
CAS Number:
Molecular Weight:
489.95
UNSPSC Code:
51101500
PubChem Substance ID:
MDL number:
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InChI

1S/C20H24ClN3O2.C4H4O4/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14;5-3(6)1-2-4(7)8/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25);1-2H,(H,5,6)(H,7,8)/b;2-1+

SMILES string

OC(=O)\C=C\C(O)=O.COc1cc(N)c(Cl)cc1C(=O)NC2CCN(CC2)Cc3ccccc3

InChI key

BCVIWCRZYPHHMQ-WLHGVMLRSA-N

assay

~95%

storage temp.

2-8°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Jaume Campdelacreu et al.
Movement disorders : official journal of the Movement Disorder Society, 19(4), 482-484 (2004-04-13)
We report on a patient who presented with a progressive supranuclear palsy (PSP) syndrome while receiving clebopride (CLB), a prokinetic drug with central antidopaminergic properties. The clinical and neurophysiological signs progressively disappeared after CLB withdrawal. To our knowledge, this is
[Acute laryngeal dystonia due to clebopride simulating allergic reaction].
Mercè Corominas Sánchez et al.
Medicina clinica, 129(6), 238-239 (2007-08-07)
Domenico Bosco et al.
Clinical neuropharmacology, 32(2), 107-108 (2009-06-11)
Dystonic reactions produce twisting and repetitive movements or abnormal posturing. Severe dystonic reactions have been shown to occur in concert with numerous medications. This report details the case of a patient who developed hemifacial dystonia as acute side reaction from
M Blanco et al.
Journal of pharmaceutical and biomedical analysis, 15(3), 329-338 (1996-12-01)
A spectrophotometric method for the simultaneous determination of the active principle and a flavouring agent in syrups containing additional excipients is proposed. The calibration matrix must include all the variability expected in the samples and this is achieved using laboratory-made
Girutz Linazasoro et al.
Movement disorders : official journal of the Movement Disorder Society, 20(2), 251-253 (2004-09-30)
We report on the case of a woman with belly dancer's syndrome. This case presented two peculiarities: (1) the condition was induced by the chronic use of clebopride, and (2) abdominal dyskinesias showed a dramatic response to the application of

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